A National Institutes of Health (NIH)-funded collaboration between scientists at Arkansas Children’s Research Institute (ACRI) and the University of Arkansas for Medical Sciences (UAMS) will help the Centers for Disease Control and Prevention (CDC) and the Arkansas Department of Health (ADH) understand more about the variants of COVID-19 circulating in the state by increasing capacity for genomic sequencing, tracking and analyses of virus samples.
The $770,000 NIH grant will be devoted to the collaboration between UAMS, Arkansas Children’s, Baptist Health, and ADH. The “Arkansas Sequencing (ArkSeq) Consortium” will be a source for samples from across the state to be used for sequencing COVID-19 variants. ACRI will provide an additional $200,000, in part from Arkansas Biosciences Institute funds, to expand sequencing capacity.
ACRI’s NIH-funded Center for Translational Pediatric Research (CTPR) and UAMS’ IDeA Network of Biomedical Research Excellence (INBRE) will lead the collaborative efforts. The grant is awarded to Alan Tackett, MD, CTPR director, professor in the UAMS College of Medicine Department of Biochemistry and Molecular Biology and deputy director for the UAMS Winthrop P. Rockefeller Cancer Institute, and Josh Kennedy, MD, associate professor in the UAMS College of Medicine Department of Pediatrics, Division of Allergy and Immunology.
Kennedy said the work will help the state understand which variants of COVID-19 are present in Arkansas and could even help identify new variants. Data ranging from demographics to collection dates, symptoms, and vaccination status will all be essential to the project, which will result in actionable data provided to the CDC and ADH.
“The big picture information that emerges from this type of detail can equip the healthcare community to respond more quickly, ultimately saving more lives and preventing some serious complications,” Kennedy said. “Combining the expertise and resources of several Arkansas health leaders will mean we help more people faster.”
Today, Arkansas has sequenced fewer than 1,000 COVID-19 samples – a total of only 0.28% of all cases. That ranks the state 48th nationally for total samples sequenced. The scientists expect to yield eight times more sequences from Arkansas for national databases, also producing additional samples for future study.