UAMS Winthrop P. Rockefeller Cancer Institute Expands OnCore to Strengthen Clinical Trials

The University of Arkansas for Medical Sciences (UAMS) Winthrop P. Rockefeller Cancer Institute has fully implemented the Advarra OnCore Clinical Trials Management System, a major investment that strengthens oversight, efficiency, and growth of cancer clinical trials.

As of Dec. 4, the Cancer Institute is live with all three Advarra modules, including OnCore, Electronic Regulatory (eReg) and Electronic Data Capture (EDC), completing a phased rollout that began July 1, 2024. Approximately 150 users across the Cancer Institute and the UAMS Translational Research Institute are now using the system to manage 303 active clinical trials and track 1,127 patients enrolled in studies.

OnCore centralizes the administration of clinical trials, helping research teams evaluate studies, manage finances, oversee regulatory compliance, streamline patient onboarding, and support day-to-day trial operations. The system integrates with Epic, UAMS’ electronic medical record system, improving coordination between clinical care and research activities.

The $2.4 million investment in OnCore, eReg and EDC, the most widely adopted clinical trials systems in the country currently used by 80% of National Cancer Institute (NCI) designed cancer centers, places the Cancer Institute and UAMS among the nation’s leading academic medical centers. Arkansas Children’s Hospital also uses OnCore to manage its clinical trials. 

Advarra’s eReg module streamlines the management and oversight of regulatory documents throughout the lifecycle of a clinical trial. The electronic platform securely stores and shares protocols, staff credentials and regulatory documents, improving accuracy and ensuring compliance. The EDC module supports fast, accurate data collection by providing real-time access to clinical trial data.

01/12/2026